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Abstract
Rising costs of classical instrumental methods of chemical analysis coupled with an increasing need for environmental monitoring has lead to the development of highly sensitive, low-cost immunochemical methods of analysis for the detection of environmental contaminants. These methods known simply as immunoassays are chemical assays which use antibodies as reagents. A target compound (such as a pesticide) is detected by an antibody which binds only to that substance. The binding efficiency can be designed to permit measurements down below the picogram (lo-l2 gram) level. Some of the assays can be performed in a complex sample matrix with little or no sample preparation. The technique allows for a rapid analysis at a relatively low cost ($5-10 per sample) compared to classical chromatographic and spectrophotometric techniques ($40=200/sample). Allied instrumentation such as low- cost photometers as well as the associated training of technical staff is much less complex and costly than classical techniques.
Citation
McMahon, Charles K. 1993. A review of promising new immunoassay technology for monitoring forest herbicides. In: Proceedings of the 46th Annual Meeting Southern Weed Science Society; 1993 January 18-20; Charlotte, NC. [Champaign, IL]: Southern Weed Science Society: 220-222.