DOSESCREEN: a computer program to aid dose placement

Kimberly C. Smith; Jacqueline L. Robertson

doi:10.2737/PSW-GTR-78

Treesearch

DOSESCREEN: a computer program to aid dose placement

Informally Refereed

Authors:

Kimberly C. Smith, Jacqueline L. Robertson

Year:

1984

Type:

General Technical Report

Station:

Pacific Southwest Research Station

DOI:

https://doi.org/10.2737/PSW-GTR-78

Source:

Gen. Tech. Rep. PSW-78. Berkeley, Calif.: U.S. Department of Agriculture, Forest Service, Pacific Southwest Forest and Range Exp. Stn. 12 p

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Abstract

Careful selection of an experimental design for a bioassay substantially improves the precision of effective dose (ED) estimates. Design considerations typically include determination of sample size, dose selection, and allocation of subjects to doses. DOSESCREEN is a computer program written to help investigators select an efficient design for the estimation of an arbitrary ED. This report establishes the statistical basis for DOSESCREEN and suggests several ways to utilize DOSESCREEN out-put. A copy of the computer program in Fortran 77 is provided so users can easily convert DOSESCREEN to their own computer system.

Keywords

bioassay, experimental design, effective doses

Citation

Smith, Kimberly C.; Robertson, Jacqueline L. 1984. DOSESCREEN: a computer program to aid dose placement. Gen. Tech. Rep. PSW-GTR-78. Berkeley, CA: U.S. Department of Agriculture, Forest Service, Pacific Southwest Forest and Range Experiment Station. 12 p.