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Abstract
Few microbes compare with the filamentous fungus Aspergillus niger in its ability to produce prodigious amounts of useful chemicals and enzymes. This fungus is the principal source of citric acid for food, beverages and pharmaceuticals and of several important commercial enzymes, including glucoamylase, which is widely used for the conversion of starch to food syrups and to fermentative feedstocks for ethanol production. Although most of these fermentation processes are well established, the underlying genetics are still poorly understood. In this issue, Pel et al. report the genome sequence of A. niger strain CBS 513.88. The availability of this sequence should provide invaluable aid toward improving the production of chemicals and enzymes in this organism.
Keywords
Nucleotide sequence,
genomes,
fungi,
industrial applications,
enzymes,
biotechnology,
genetic engineering,
Aspergillus niger,
genetics,
biodegradation,
gene expression,
microbial metabolism,
regulation,
fermentation,
citric acid,
chemical engineering,
decay fungi,
glucoamylase
Citation
Cullen, Dan. 2007. The genome of an industrial workhorse : sequencing of the filamentous fungus Aspergillus niger offers new opportunities for the production of specialty chemicals and enzymes. Nature biotechnology. Vol. 25, no. 2 (Feb. 2007): Pages 189-190
