RNA-editing in Basidiomycota, revisited

Abstract

In fungi, adenosine-to-inosine (A-to-I) RNA-editing was shown to occur during sexual development and fruiting body formation in filamentous ascomycetes Fusarium graminearum, F. verticillioides, Neurospora crassa, Sordaria macrospora, and Pyronema confluens (Pezizomycotina) [1, 2], but absent during meiosis in the fission yeast Schizosaccharomyces pombe (Taphrinomycotina) [2]. In Basidiomycota, the first RNA-editing report was from Ganoderma lucidum, a mushroom-forming species of Polyporales, also during fruiting body formation [3]. Afterwards, Wu et al. reported RNA-editing events in vegetative mycelia of five other species of Polyporales [4, 5]. It was noted that the editing patterns of both G. lucidum and the five Polyporales fungi were not only different from the typical A-to-I editing but also showed that transitions (A- > G, G- > A, C- > U, U- > C) were preferred over transversions, leading mainly to synonymous changes in contrast to missense changes found in filamentous ascomycetes [3–5].

Citation

Min, Byoungnam; Wu, Baojun; Gaskell, Jill; Zhang, Jiwei; Toapanta, Christina; Ahrendt, Steven; Blanchette, Robert A.; Master, Emma; Cullen, Daniel; Hibbett, David S.; Grigoriev, Igor V. 2021. RNA-editing in Basidiomycota, revisited. ISME Communications. 1(1): 499. https://doi.org/10.1038/s43705-021-00037-9.